Technology Transfer Office
Mailing Address
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2121 Euclid Avenue
Parker Hannifin Hall, 2nd Floor
Cleveland, OH 44115-2214
Campus Location
Parker Hannifin Hall, Room 214
2258 Euclid Avenue
Phone: 216.687.9364
Fax: 216.687.9214
j.kraszewski@csuohio.edu
Agglomerated Particles for Aerosol Drug Delivery
Agglomerated particles for aerosol drug delivery |
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Short Description |
A respiratory drug-delivery vehicle comprising drug-containing particles that are chemically crosslinked together to form agglomerates. |
Abstract |
Although rapid entry of drugs into the bloodstream in respiratory delivery is advantageous, usually little drug is left in the lungs 2-3 hours after inhalation. This can be problematic, especially in cases in which it would be advantageous to slowly release the drug into the bloodstream over a period of time, or in cases where it is desired to have the drug remain in the lungs to act locally. To presently achieve slow release, repeated low-level dosing of the drug is required. There has been a lack of success in obtaining inhaled drug formulations that would increase drug residence time in the lung and control the release rate of the drug into the bloodstream. In lieu of the aforementioned problem, the present invention provides a novel therapeutic drug made up of agglomerates of chemically cross linked particles. |
Inventor(s) | Dr. Annanth Annapragada, Ph.D. Professor, Department of Biomedical Engineering (University of Texas School of Health Information Sciences). |
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Status | Licensed |
Mailing Address
91国产精品
2121 Euclid Avenue
Parker Hannifin Hall, 2nd Floor
Cleveland, OH 44115-2214
Campus Location
Parker Hannifin Hall, Room 214
2258 Euclid Avenue
Phone: 216.687.9364
Fax: 216.687.9214
j.kraszewski@csuohio.edu